Ketamine molecule:

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Ketamine Clinical Trials


Ketamine In Thoracic Surgery (KITS) Trial


To see complete record on clinicaltrials.gov, please visit this link

Id: NCT00504725

Organisation Name: Duke University

Overal Status: Completed

Start Date: July 2007

Last Update: July 25, 2014

Lead Sponsor: Duke University

Brief Summary: The primary aim of the study is to demonstrate a reduction in circulating interleukin 6 levels at 4 and 24 hours after completion of lobectomy (either VATS or open). The null hypothesis (H0) is thus that there is no difference in circulating interleukin 6 levels when patients are given either ketamine or placebo (0.9% saline in equivalent volume). The alternative (two tailed) hypothesis (HA) if the null is disproved is that ketamine leads to significantly different levels of interleukin 6 at 4 and 24 hours after completion of surgery. We plan to randomize 40 patients to receive either ketamine or placebo, in a block of 4 randomization design stratified by whether surgery is performed by VATS or open lobectomy.

Conditions:
  • Lung Cancer


Total execution time in seconds: 0.42943501472473