Ketamine molecule:

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Ketamine Clinical Trials

Reduction Of Chronic Post-surgical Pain with Ketamine – A Pilot Study

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Id: ACTRN12614000247673

Organisation Name: Austin Health

Overal Status: Completed

Brief Summary: There is a well established physiological basis for the proposition that a potent NMDA receptor antagonist such as the widely available drug ketamine given peri-operatively may reduce the development of chronic postsurgical pain in patients undergoing major surgery, and this proposition is supported by available data pooled from small placebo controlled published studies, and a large study on N2O. The potential benefits of this in reducing the burden of chronic pain in the community are substantial.
A large multicentre randomized trial is needed in patients undergoing major surgery to determine whether chronic post-surgical pain is reduced using intravenous ketamine given peri-operatively.

  • Australia

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