Dimethyltryptamine molecule:

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DMT Clinical Trials


Effects of Dimethyltryptamine (DMT) in Healthy Subjects: A Placebo-controlled Cross-over Study


To see complete record on clinicaltrials.gov, please visit this link

Id: NCT04353024

Organisation Name: University Hospital, Basel, Switzerland

Overal Status: Not yet recruiting

Start Date: October 1, 2020

Last Update: April 29, 2020

Lead Sponsor: University Hospital, Basel, Switzerland

Brief Summary: N,N-dimethyltryptamine (DMT) is a naturally-occurring psychedelic substance widely used in recreational and spiritual settings. DMT can be used as a tool to induce an altered state of consciousness of interest in psychological and psychiatric research. DMT is rapidly metabolized by monoamine oxidase (MAO) A. Therefore, it is inactive when administered orally and has a very short duration of action when administered parenterally (<20 min).Therefore, an intravenous administration regime including a bolus and maintenance perfusion has been proposed to induce a stable and prolonged DMT experience allowing to study the psychological and autonomic acute effects of DMT. This administration allows to induce and end an altered state safely and quickly. The goal of the present study is to experimentally test different intravenous DMT administration schedules to investigate the subjective and autonomic effects of DMT in healthy subjects.

Conditions:
  • Healthy


Total execution time in seconds: 0.21048617362976